Glucose-6-Phosphate Dehydrogenase (G6PD) Test

The Glucose-6-Phosphate Dehydrogenase (G6PD) Test measures the activity of the G6PD enzyme in red blood cells to identify G6PD deficiency, an inherited condition that can increase susceptibility to hemolytic anemia. Individuals with G6PD deficiency may experience the breakdown of red blood cells after exposure to certain medications, infections, or foods such as fava beans. This test is commonly used to evaluate unexplained anemia or jaundice, investigate episodes of hemolysis, and determine whether medications that can trigger hemolysis may be used safely. Results help guide diagnosis, treatment decisions, and long-term management of G6PD deficiency.