Erythrocyte sedimentation rate (ESR)

Erythrocyte sedimentation rate (ESR) measures the rate at which red blood cells settle. Larger clumps of red blood cells will settle more rapidly, resulting in an elevated ESR. These large clusters of erythrocytes tend to form when there is elevated blood clotting going on, which typically coincides with more inflammatory processes.

Inflammation is a part of the immune system that is geared towards the breakdown of cells, foreign matter and microorganisms. While inflammation is imperative for resisting infections and overcoming tissue damage, it should be resolved quickly thereafter. Inflammation can drive the stress systems, contribute to oxidative stress and impair metabolism, and thus plays a key role in various health issues if chronically activated.