Interleukin 6 (IL-6) is a pro-inflammatory cyotkine. It is produced by immune cells in response to infection in order to signal to other components of the immune system to initiate the response to clear out pathogens, dead or dysfunctional cells. It is also produced in the fat tissue, and levels rise with obesity.
Inflammation is a part of the immune system that is geared towards the breakdown of cells, foreign matter and microorganisms. While inflammation is imperative for resisting infections and overcoming tissue damage, it should be resolved quickly thereafter. Inflammation can drive the stress systems, contribute to oxidative stress and impair metabolism, and thus plays a key role in various health issues if chronically activated.
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