Ferritin

Ferritin is the primary protein that stores iron in cells. Its levels being elevated in the serum (which does not contain cells) indicates cell damage and inflammation, as the protein “leaks” into the serum and also participates in the inflammatory response. High levels can also indicate iron overload, while low levels can be the result of iron deficiency. 

Iron is an essential mineral that holds a unique place in our body. On one hand, iron is considered the most common nutritional deficiency, yet, many health issues involve an excess of iron. This is primarily because iron types, absorption, transport and utilization is are multifaceted issues that are difficult to capture simply. Iron deficiency can create symptoms such as fatigue and brain fog, while excess iron can drive tissue damage and inflammation, resulting in a multitude of symptoms. Long term iron status is important to monitor for disease prevention and longevity as well, since countless age related conditions are predicted by either iron deficiency or excess.

Inflammation is a part of the immune system that is geared towards the breakdown of cells, foreign matter and microorganisms. While inflammation is imperative for resisting infections and overcoming tissue damage, it should be resolved quickly thereafter. Inflammation can drive the stress systems, contribute to oxidative stress and impair metabolism, and thus plays a key role in various health issues if chronically activated.